Dermatologist Designed Skin Care Made Simple


Serum 6

Your six-in-one, essential serum.

Offering intense hydration, smoothing, brightening, and protection from pollution and environmental factors, Serum 6 contains all you need to optimize the health and appearance of your skin, delivering glowing, youthful results.

The more you use it, the better it works.

Contains 15+ medical-grade vitamins, antioxidants, peptides, amino acids, probiotics and plant stem cell extracts in an opulent, silky texture for maximum performance.

The 6 Superstar Actives

Antioxidants counteract the harmful effects of environmental pollution, free radicals and UV radiation for optimal long-term skin health.

The science behind it:

Our plant-based antioxidant blend is formulated with Vitamin C, Niacinamide, Alpine Edelweiss Flower, French Maritime Pine Tree, Malus Domestica Fruit Cell Culture Extract, Shiitake Mushroom Extract, and Avena Sativa. Vitamin C boosts collagen production, protects from free radicals and environmental toxins, and brightens skin. Alpine Edelweiss Flower suppresses skin wrinkling and inflammation. French Maritime Pine Tree recycles oxidized Vitamin C so it can be used again while also increasing skin elasticity and hydration.

Peptides boost production of six major components of the skin matrix, resulting in a more even skin tone and helping to reduce the appearance of wrinkles.

The science behind it:

Palmitoyl Tripeptide-38, also known as Matrixyl synthe’6, boosts production of six major components of the skin matrix: Collagen I, III, and IV, fibronectin, hyaluronic acid and laminin 5, resulting in more even skin and fewer wrinkles, especially on the forehead and around the eyes.

Multi-molecular Weight Hyaluronic Acid hydrates, smooths and plumps by penetrating various skin layers.

The science behind it:

Multi-molecular weight hyaluronic acid penetrates to varying levels of the skin, performing different functions at each: hydrating deep while smoothing and plumping closer to the surface. Sodium hyaluronate is a low molecular weight hyaluronic acid that has the ability to penetrate into deep layers of the skin, attracting and binding up to 1000 times its weight in water to hydrate, plump and reduce the appearance of wrinkles.Hydrolyzed hyaluronic acid is higher weight, working on the skin’s surface to attract and bind up to 1000 times its own weight in water to help hydrate the skin at its surface.

Plant-derived Stem Cells enhance the vitality of skin cells, increase skin density and reduce the appearance of wrinkles.

The science behind it:

Malus Domestica Fruit Cell Culture Extract is derived from a rare Swiss apple variety, and is shown to help skin cells maintain capacity to build new tissues, increase skin density, increase vitality of epidermal stem cells, and reduce the appearance of wrinkles. Pseudoaltermonas Ferment Extract is found in deep seawater. This soothing and anti-inflammatory botanical helps skin retain moisture and promotes skin regeneration by stimulating production of collagen and elastin.

Probiotics increase skin’s defense mechanisms and reduce redness. 

The science behind it:

Lactobacillus Ferment Lysate Filtrate, a soothing probiotic, has been shown to increase skin’s defense mechanisms and decrease irritation and redness. In vitro, it has also proven to promote oxygen uptake, collagen production and synthesis of ATP (the energy molecule our body produces and uses).

Niacinamide brightens skin tone and minimizes the appearance of pores.

The science behind it:

When applied to the skin, this powerful antioxidant helps to minimize enlarged pores, brighten skin tone, minimize dullness, and strengthen the skin barrier. Niacinamide functions as an anti-inflammatory and helps skin to retain moisture.


Serum 6 should be applied to clean skin twice daily after cleansing. Top it off with your favorite sunscreen during the day, or may be used with a retinoid at night.

For all skin types.

Customer Reviews

Based on 49 reviews
Marsha Everett
Maei serum

The serum feels nice on my skin, but so far I haven't noticed any difference. I haven't used it very long, so I will just be patient.

Kelsey Lawson

Serum 6

courtney woodworth
The best serum I have tried for sun damaged skin

This serum is incredible. It is the only serum I have tried that truly hydrates my very dry, sensitive skin. I love that it has no added fragrance and is just pure power-packed ingredients. I have significant photoaging and melasma, and it really helps make my skin appear younger and less sun damaged. Plain hyaluronic acids and the other luxury serums on the market don't hold a candle to this one. A must have for supple hydrated skin.


love it!

Noticeable Difference

I have to take a lot of hormones for a medical condition so I get frequent adult acne, especially cystic acne. It's always been a struggle for me to find a face care routine that works well for me, especially since I have sensitive skin which also frequently dries out since I live in a very hot, dry climate. I'm happy to say Maei MD works for me! The serum is very easy to use and a little goes a long way. I've been using it for over 6 months now and it's very easy to incorporate into my current routine. It doesn't inflame or irritate my skin at all and actually feels quite soothing after application. I started to notice the improvement on my skin quickly and if I skipped usage the impact was almost immediate. What definitely set me over the edge though is that I suddenly started to get MANY compliments on my skin, even though it's summer! I've had multiple friends, business associates, and even strangers now stop me and ask what's my secret. I've proudly been sharing Maei MD. I only just had to order my first refill, but I feel I've been convinced of the magic and will be a continuing return customer. Highly recommend!